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Angioedema and angiotensin-II receptor blockers

admin — Tue, 06 Oct 2009 10:11:34 +0000

Angioedema is a rare serious adverse drug reaction (ADR) to angiotensin-converting enzyme inhibitors (ACE-I), with an incidence of 0.1% to 1.0%. If untreated it can be life-threatening. Debate exists over the safety of switching to an angiotensin-II receptor blocker (ARB), due to case reports of angioedema, and the mechanism of ARB-associated angioedema. The DoTS system of ADR classification provides a structured template for examining the Dose and Time relationship, and potential Susceptabilities to an ADR.

Here is a poster we are presenting at the International Society of Pharmacovigilance conference this week.

Angioedema associated with angiotensin-II receptor blockers: a DoTS classification
and analysis [PDF].

Recent Research Findings

admin — Tue, 11 Dec 2007 13:56:33 +0000

The following are three posters this unit recently presented at ISOP 2007 in October of this year:

Cox AR, Anton C, Marriott JF, Ferner RE. The paradox of low prescribers who are high reporters: correlates of spontaneous reporting of adverse drug reactions within primary care. Drug Safety 2006; 30(10): 977-978
(Presented at the 7th Annual Meeting of ISoP Bournemouth – UK, 21-24 October 2009)

Download PDF of Poster

McDowell SE, Coleman JJ, Ferner RE. Rhabdomyolysis and statins – an analysis of spontaneous case reports using a three-diensional classification scheme. Drug Safety 2006; 30(10): 979
(Presented at the 7th Annual Meeting of ISoP Bournemouth – UK, 21-24 October 2009)

Download PDF of Poster

Ormerod S, McDowell SE, Coleman JJ, Ferner RE. Ethnic differences in the risks of adverse reactions to drugs used in the treatment of psychoses: systematic review and meta-analysis. Drug Safety 2006; 30(10): 975-976
(Presented at the 7th Annual Meeting of ISoP Bournemouth – UK, 21-24 October 2009)

Download PDF of Poster

ISOP 2006

admin — Fri, 20 Oct 2006 08:42:19 +0000

The Yellow Card Centre West Midlands staff attended the 6th annual conference of the International Society of Pharmacovigilance in Liege, Belgium. We displayed three research posters and delivered an oral presentation on a variety of subjects related to drug safety.

Download Presentation

Download poster

Chief Pharmacists’ views of Adverse Drug Reaction Reporting.

admin — Wed, 03 Nov 2004 13:08:13 +0000

You can now download a PDF version of our poster presented at the International Society of Pharmacovigilance (ISOP) Annual Meeting in Dublin: Message from the top: Chief Pharmacists’ views of Adverse Drug Reaction Reporting.

Anthony Cox presents the poster at the 2004 ISOP meeting in Dublin.