Archive for March, 2010

Drug Safety Update: Volume 3, Issue 8, March 2010

admin March 11th, 2010

The MHRA have published the March issue of Drug Safety Update, including:

  • Natalizumab (Tysabri): risk of progressive multifocal leukoencephalopathy increases after two years of therapy.
  • Fluoxetine: possible small risk of congenital cardiac defects, similar to that with paroxetine.
  • Sirolimus: different immunoassays for therapeutic drug monitoring—risk of incorrect dose adjustment.
  • Drug Safety Update gains NHS Evidence accreditation.
  • MHRA conference for doctors in training.
  • Patient Information Leaflet of the month: Human Varicella-Zoster Immunoglobulin vaccine.