Recent MHRA safety messages

admin June 5th, 2007

Cases of endophthalmitis, eye inflammation, increased intraocular pressure, and visual disturbances after unapproved route of intraocular administration of Adcortyl/Kenalog injections (triamcinolone acetonide).

Occurrence of tracheoesophaegeal fistula during study of chemotherapy plus radiotherapy plus Avastin in patients with limited-stage small-cell lung cancer (unapproved indication) with Avastin (bevacizumab).

Genotropin (somatropin): Small electronic calculators for auxology measurement and dosing of growth hormone may overestimate body surface area.

MHRA statement on cardiac safety of rosiglitazone (brand name Avandia).

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