Piroxicam: GI and skin reactions
admin June 26th, 2007
Restrictions have been placed on the use of piroxicam. First prescriptions should not be for longer than 2 weeks and it can only be used in patients with osteoarthritis, rheumatoid arthritis, or, ankylosing spondylitis as second line treatment.
The European Medicines Agency (EMEA) has recommended restrictions on the use of piroxicam containing medicinal products because of the risk of gastrointestinal side effects and serious skin reactions. The Agency’s Committee for Medicinal Products for Human Use (CHMP) concluded that piroxicam should no longer be used for treatment of short-term painful and inflammatory conditions.
Piroxicam can still be prescribed for the symptomatic relief of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. However it should not be the first choice of non-steroidal anti-inflammatory drug (NSAID) treatment in these conditions.
More at EMEA in PDF format.
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