admin October 24th, 2006
The American Association of Oral and Maxillofacial Surgeons have produced a position paper on Bisphosphonate-Related Osteonecrosis of the Jaws. The paper gives an overview of the risks, possible risk factors, and management strategies for the condition.
Link Here. [PDF 104kb]
[Via Reactions]
admin October 20th, 2006
The FDA have issued warnings about cardiac adverse events related to imatinib mesylate (Gleevec):
Novartis and FDA notified healthcare professionals about revisions to the PRECAUTIONS section of the prescribing information, describing the occasional occurrence of severe congestive heart failure and left ventricular dysfunction in patients taking Gleevec. Most of the patients with reported cardiac events had other co-morbidities and risk factors, including advanced age and previous medical history of cardiac disease.
Patients with cardiac disease or risk factors for cardiac failure should be monitored carefully and any patients with signs or symptoms consistent with cardiac failure should be evaluated and treated.
admin October 20th, 2006
The Yellow Card Centre West Midlands staff attended the 6th annual conference of the International Society of Pharmacovigilance in Liege, Belgium. We displayed three research posters and delivered an oral presentation on a variety of subjects related to drug safety.
